FRAT1, FRAT regulator of WNT signaling pathway 1

FRAT1, FRAT regulator of WNT signaling pathway 1

• The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008]

• Gene Synonyms (proto-oncogene FRAT1, FRAT-1, FRAT1, WNT signaling pathway regulator, frequently rearranged in advanced T-cell lymphomas 1,)
• NCBI Gene ID: 10023
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92837
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FRAT regulator of WNT signaling pathway 1 interacts with:

• G protein-coupled receptor associated sorting protein 2
  laminin subunit gamma 3
  lectin, mannose binding 2
  rabaptin, RAB GTPase binding effector protein 2
  tudor domain containing 7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.