RCAN2, regulator of calcineurin 2

RCAN2, regulator of calcineurin 2

• This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (calcipressin-2, Down syndrome candidate region 1-like 1, Down syndrome critical region gene 1-like 1, myocyte-enriched calcineurin-interacting protein 2, thyroid hormone-responsive (skin fibroblasts), thyroid hormone-responsive protein ZAKI-4, CSP2, DSCR1L1, MCIP2, RCN2, ZAKI-4, ZAKI4,)
• NCBI Gene ID: 10231
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B2R612
  UNIPROT ID#>>Q14206
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulator of calcineurin 2 interacts with:

• acidic residue methyltransferase 1
  cornulin
  serpin family A member 12
  trafficking from ER to golgi regulator
  zymogen granule protein 16B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.