TRDMT1, tRNA aspartic acid methyltransferase 1

TRDMT1, tRNA aspartic acid methyltransferase 1

• This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]

• Gene Synonyms (tRNA (cytosine(38)-C(5))-methyltransferase, DNA (cytosine-5)-methyltransferase-like protein 2, DNA MTase homolog HsaIIP, DNA cytosine-5 methyltransferase 2, DNA methyltransferase-2, tRNA (cytosine-5-)-methyltransferase, DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1,)
• NCBI Gene ID: 1787
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DQZ2
  UNIPROT ID#>>A0A0U1U562
  UNIPROT ID#>>Q7Z3E4
  UNIPROT ID#>>O14717
  UNIPROT ID#>>Q6ICS7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tRNA aspartic acid methyltransferase 1 interacts with:

• 1,4-alpha-glucan branching enzyme 1
  BICD cargo adaptor 2
  COP9 signalosome subunit 6
  DEAD-box helicase 24
  dynein cytoplasmic 1 light intermediate chain 1
  eukaryotic translation elongation factor 1 alpha 1
  ligand dependent nuclear receptor interacting factor 1
  nuclear factor related to kappaB binding protein
  protein phosphatase 1 regulatory subunit 12A
  protein phosphatase 1 regulatory subunit 16B
  RNA binding motif protein 48
  SET domain bifurcated histone lysine methyltransferase 1
  small nuclear ribonucleoprotein D3 polypeptide
  syntaxin 1A
  TBC1 domain family member 2B
  transmembrane channel like 6
  unc-119 lipid binding chaperone
  UTP14A small subunit processome component

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.