ELK3, ETS transcription factor ELK3

ELK3, ETS transcription factor ELK3

• This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (ERP, NET, SAP-2, SAP2, ETS domain-containing protein Elk-3, ELK3, ETS transcription factor, ELK3, ETS-domain protein (SRF accessory protein 2), ETS-related protein ERP, ETS-related protein NET, SRF accessory protein 2, serum response factor accessory protein 2,)
• NCBI Gene ID: 2004
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RBE2
  UNIPROT ID#>>P41970
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ETS transcription factor ELK3 interacts with:

• BPI fold containing family A member 1
  DNA topoisomerase I
  heterogeneous nuclear ribonucleoprotein L
  inhibitor of DNA binding 2
  mitogen-activated protein kinase 8
  mitogen-activated protein kinase 9
  prefoldin subunit 5
  protein inhibitor of activated STAT 1
  Sp4 transcription factor
  transcription factor 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.