PPM1E, protein phosphatase, Mg2+/Mn2+ dependent 1E

PPM1E, protein phosphatase, Mg2+/Mn2+ dependent 1E

• This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

• Gene Synonyms (CaMKP-N, POPX1, PP2CH, caMKN, protein phosphatase 1E, ca(2+)/calmodulin-dependent protein kinase phosphatase N, caMKP-nucleus, nuclear calmodulin-dependent protein kinase phosphatase, partner of PIX 1, partner of PIX-alpha, partner of PIXA, protein phosphatase 1E (PP2C domain containing),)
• NCBI Gene ID: 22843
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A7E2X1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase, Mg2+/Mn2+ dependent 1E interacts with:

• DISC1 scaffold protein
  family with sequence similarity 83 member H
  isoprenylcysteine carboxyl methyltransferase
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  proteasome activator subunit 3 interacting protein 1
  proteasome assembly chaperone 3
  proteasome assembly chaperone 4
  schlafen family member 11
  syntaxin 17
  TAR DNA binding protein
  TRAF2 and NCK interacting kinase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.