PIP5K1C, phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

PIP5K1C, phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

• This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010]

• Gene Synonyms (LCCS3, PIP5K-GAMMA, PIP5K1-gamma, PIP5Kgamma, phosphatidylinositol 4-phosphate 5-kinase type-1 gamma, diphosphoinositide kinase, phosphatidylinositol-4-phosphate 5-kinase, type I, gamma, ptdIns(4)P-5-kinase 1 gamma, type I PIP kinase,)
• NCBI Gene ID: 23396
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60331
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma interacts with:

• coenzyme Q2, polyprenyltransferase
  haloacid dehalogenase like hydrolase domain containing 2
  La ribonucleoprotein 7, transcriptional regulator
  lysosomal protein transmembrane 4 beta
  phosphatidylinositol-4-phosphate 5-kinase like 1
  SMAD specific E3 ubiquitin protein ligase 1
  sorting nexin 5
  talin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.