DKK3, dickkopf WNT signaling pathway inhibitor 3

DKK3, dickkopf WNT signaling pathway inhibitor 3

• This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dickkopf-related protein 3, RIG-like 5-6, RIG-like 7-1, dickkopf 3 homolog, dickkopf homolog 3, dickkopf-3, dkk-3, hDkk-3, regulated in glioma, REIC, RIG,)
• NCBI Gene ID: 27122
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F6SYF8
  UNIPROT ID#>>Q9UBP4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dickkopf WNT signaling pathway inhibitor 3 interacts with:

• assembly factor for spindle microtubules
  ATPase family AAA domain containing 3C
  carbohydrate sulfotransferase 12
  DnaJ heat shock protein family (Hsp40) member C30
  fizzy and cell division cycle 20 related 1
  golgi reassembly stacking protein 1
  inhibin subunit beta E
  lon peptidase 2, peroxisomal
  MAP7 domain containing 1
  myosin VC
  SPARC related modular calcium binding 1
  sulfatase 2
  SUMO specific peptidase 5
  TNFAIP3 interacting protein 2
  ubiquilin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.