IL36A, interleukin 36 alpha

IL36A, interleukin 36 alpha

• The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]

• Gene Synonyms (interleukin-36 alpha, FIL1 epsilon, IL-1 epsilon, IL-1F6 (FIL-1-epsilon), interleukin 1 family, member 6 (epsilon), interleukin-1 epsilon, interleukin-1 family member 6, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6,)
• NCBI Gene ID: 27179
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHA7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 36 alpha interacts with:

• actin beta like 2
  chromosome transmission fidelity factor 8
  nanos C2HC-type zinc finger 2
  ring finger protein 20
  small integral membrane protein 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.