GPLD1, glycosylphosphatidylinositol specific phospholipase D1

GPLD1, glycosylphosphatidylinositol specific phospholipase D1

• Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]

• Gene Synonyms (phosphatidylinositol-glycan-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, PI-G PLD, glycoprotein phospholipase D, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1, PLD,)
• NCBI Gene ID: 2822
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P80108
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glycosylphosphatidylinositol specific phospholipase D1 interacts with:

• egl-9 family hypoxia inducible factor 1
  hypoxia inducible factor 1 subunit alpha
  TAFA chemokine like family member 4
  von Hippel-Lindau tumor suppressor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.