GSTT1, glutathione S-transferase theta 1

GSTT1, glutathione S-transferase theta 1

• The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]

• Gene Synonyms (glutathione S-transferase theta-1, GST class-theta-1, glutathione transferase T1-1,)
• NCBI Gene ID: 2952
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q4GZS9
  UNIPROT ID#>>Q4W251
  UNIPROT ID#>>A0A0G2JRN4
  UNIPROT ID#>>A0A0G2JRQ5
  UNIPROT ID#>>P30711
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutathione S-transferase theta 1 interacts with:

• glutathione S-transferase omega 1
  hemoglobin subunit alpha 2
  hemoglobin subunit beta
  histidine triad nucleotide binding protein 1
  leucine rich adaptor protein 1
  LRP2 binding protein
  midline 1
  myosin light chain kinase 2
  serine protease 2
  sirtuin 2
  SprT-like N-terminal domain
  zinc finger matrin-type 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.