HOXC6, homeobox C6

HOXC6, homeobox C6

• This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein Hox-C6, homeo box 3C, homeo box C8 protein, homeobox protein CP25, homeobox protein HHO.C8, homeobox protein Hox-3C, CP25, HHO.C8, HOX3, HOX3C,)
• NCBI Gene ID: 3223
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09630
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

homeobox C6 interacts with:

• BCAR3 adaptor protein, NSP family member
  checkpoint kinase 2
  insulin like growth factor 1 receptor
  protein tyrosine phosphatase receptor type J
  TNFAIP3 interacting protein 2
  transforming growth factor beta 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.