AGFG2, ArfGAP with FG repeats 2

AGFG2, ArfGAP with FG repeats 2

• This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013]

• Gene Synonyms (arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain binding protein-related, arf-GAP domain and FG repeats-containing protein 2, nucleoporin, rev/Rex activation domain-binding protein related, HRBL, RABR,)
• NCBI Gene ID: 3268
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A4D2D6
  UNIPROT ID#>>O95081
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ArfGAP with FG repeats 2 interacts with:

• epidermal growth factor receptor pathway substrate 15
  epidermal growth factor receptor pathway substrate 15 like 1
  epidermal growth factor receptor pathway substrate 15-like 1
  exportin 1
  intersectin 1
  pleckstrin homology domain containing A4
  StAR related lipid transfer domain containing 7
  tripartite motif containing 25
  tripartite motif containing 68

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.