SP110, SP110 nuclear body protein

SP110, SP110 nuclear body protein

• The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (sp110 nuclear body protein, interferon-induced protein 41, 30kD, interferon-induced protein 41/75, interferon-induced protein 75, 52kD, phosphoprotein 41, phosphoprotein 75, speckled 110 kDa, transcriptional coactivator Sp110, IFI41, IFI75, IPR1, VODI,)
• NCBI Gene ID: 3431
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HB58
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SP110 nuclear body protein interacts with:

• BUB1, mitotic checkpoint serine/threonine kinase
  centrosomal protein 43
  H4 clustered histone 1
  karyopherin subunit beta 1
  kinesin family member 13B
  kinesin family member 22
  mitotic spindle organizing protein 2
  NADH:ubiquinone oxidoreductase core subunit V2
  nucleosome assembly protein 1 like 2
  O-sialoglycoprotein endopeptidase
  survival of motor neuron 1, telomeric
  THO complex 1
  thymidine kinase 1
  timeless circadian clock 1
  transthyretin
  TSC22 domain family member 1
  tumor protein p53 binding protein 1
  ubiquitin specific peptidase 7
  vir like m6A methyltransferase associated
  zinc finger and SCAN domain containing 26
  zinc finger and SCAN domain containing 9

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.