IL13RA1, interleukin 13 receptor subunit alpha 1

IL13RA1, interleukin 13 receptor subunit alpha 1

• The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

• Gene Synonyms (interleukin-13 receptor subunit alpha-1, CD213a1 antigen, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL13 receptor alpha-1 chain, cancer/testis antigen 19, interleukin 13 receptor, alpha 1, CD213A1, CT19, IL-13Ra, NR4,)
• NCBI Gene ID: 3597
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P78552
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 13 receptor subunit alpha 1 interacts with:

• amyloid beta precursor protein binding family A member 3
  mitogen-activated protein kinase kinase kinase kinase 3
  Rap1 GTPase-GDP dissociation stimulator 1
  TRAF3 interacting protein 1
  transmembrane protein 39B
  tyrosine kinase 2

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