AFF3, AF4/FMR2 family member 3

AFF3, AF4/FMR2 family member 3

• This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (LAF4, MLLT2-like, AF4/FMR2 family member 3, MLLT2-related protein, lymphoid nuclear protein 4, lymphoid nuclear protein related to AF4, protein LAF-4,)
• NCBI Gene ID: 3899
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NAP7
  UNIPROT ID#>>P51826
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

AF4/FMR2 family member 3 interacts with:

• coiled-coil domain containing 8
  cullin 9
  MLLT3 super elongation complex subunit
  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.