LCAT, lecithin-cholesterol acyltransferase

LCAT, lecithin-cholesterol acyltransferase

• This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008]

• Gene Synonyms (phosphatidylcholine-sterol acyltransferase, 1-alkyl-2-acetylglycerophosphocholine esterase, PAF acetylhydrolase, phosphatidylcholine--sterol O-acyltransferase, phospholipid-cholesterol acyltransferase, platelet-activating factor acetylhydrolase, testicular secretory protein Li 24,)
• NCBI Gene ID: 3931
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P04180
  UNIPROT ID#>>A0A140VK24
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lecithin-cholesterol acyltransferase interacts with:

• exosome component 10
  phosphoinositide kinase, FYVE-type zinc finger containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.