LRPAP1, LDL receptor related protein associated protein 1

LRPAP1, LDL receptor related protein associated protein 1

• This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

• Gene Synonyms (A2MRAP, A2RAP, HBP44, MRAP, MYP23, RAP, alpha-2-MRAP, alpha-2-macroglobulin receptor-associated protein, 39 kDa receptor-associated protein, low density lipoprotein receptor-related protein associated protein 1, low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1),)
• NCBI Gene ID: 4043
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30533
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

LDL receptor related protein associated protein 1 interacts with:

• calreticulin 3
  DNA polymerase alpha 2, accessory subunit
  ETS variant transcription factor 7
  LDL receptor related protein 1B
  LDL receptor related protein 8
  ligand dependent nuclear receptor corepressor
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 3
  protein phosphatase, Mg2+/Mn2+ dependent 1G
  Raf-1 proto-oncogene, serine/threonine kinase
  ral guanine nucleotide dissociation stimulator
  RAN binding protein 2
  reticulon 4
  Rho associated coiled-coil containing protein kinase 2
  ring finger protein 4
  sortilin 1
  sortilin related receptor 1
  tectonic family member 1
  tectonic family member 3
  tripartite motif containing 25
  tumor protein p53
  very low density lipoprotein receptor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.