MEFV, MEFV innate immuity regulator, pyrin

MEFV, MEFV innate immuity regulator, pyrin

• This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FMF, MEF, PAAND, TRIM20, pyrin, MEFV, pyrin innate immunity regulator, Mediterranean fever, marenostrin,)
• NCBI Gene ID: 4210
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15553
  UNIPROT ID#>>D2DTW2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MEFV innate immuity regulator, pyrin interacts with:

• autophagy related 16 like 1
  beclin 1
  component of oligomeric golgi complex 5
  GABA type A receptor associated protein like 1
  GABA type A receptor associated protein like 2
  GABA type A receptor-associated protein
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 gamma
  NLR family pyrin domain containing 3
  proline-serine-threonine phosphatase interacting protein 1
  protein kinase D2
  PYD and CARD domain containing
  SIVA1 apoptosis inducing factor
  unc-51 like autophagy activating kinase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.