PDE6H, phosphodiesterase 6H

PDE6H, phosphodiesterase 6H

• This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A). [provided by RefSeq, Mar 2010]

• Gene Synonyms (retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, phosphodiesterase 6H, cGMP-specific, cone, gamma, ACHM6, RCD3,)
• NCBI Gene ID: 5149
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13956
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphodiesterase 6H interacts with:

• coactosin like F-actin binding protein 1
  POU class 6 homeobox 2
  protein kinase AMP-activated non-catalytic subunit beta 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.