PDE1B, phosphodiesterase 1B

PDE1B, phosphodiesterase 1B

• The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

• Gene Synonyms (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, 63 kDa Cam-PDE, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase, calmodulin-stimulated phosphodiesterase PDE1B1, cam-PDE 1B, epididymis secretory sperm binding protein Li 79p, phosphodiesterase 1B, calmodulin-dependent, presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B, HEL-S-79p, PDE1B1, PDES1B,)
• NCBI Gene ID: 5153
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z364
  UNIPROT ID#>>A0A024RB59
  UNIPROT ID#>>B3KX78
  UNIPROT ID#>>B4DK72
  UNIPROT ID#>>Q01064
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphodiesterase 1B interacts with:

• protection of telomeres 1
  ubiquitin protein ligase E3A

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