PPA1, inorganic pyrophosphatase 1

PPA1, inorganic pyrophosphatase 1

• The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008]

• Gene Synonyms (inorganic pyrophosphatase, PPase, cytosolic inorganic pyrophosphatase, diphosphate phosphohydrolase, epididymis secretory sperm binding protein Li 66p, inorganic diphosphatase 1, pyrophosphatase (inorganic) 1, pyrophosphatase 1, pyrophosphate phospho-hydrolase, HEL-S-66p, IOPPP, PP, PP1, SID6-8061,)
• NCBI Gene ID: 5464
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15181
  UNIPROT ID#>>V9HWB5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

inorganic pyrophosphatase 1 interacts with:

• AAR2 splicing factor
  anterior gradient 2, protein disulphide isomerase family member
  aryl hydrocarbon receptor interacting protein
  cell division cycle 73
  chromosome 11 open reading frame 54
  copper chaperone for superoxide dismutase
  cytochrome c oxidase assembly factor 7 (putative)
  dimethylarginine dimethylaminohydrolase 2
  dual specificity phosphatase 13
  elongation factor Tu GTP binding domain containing 2
  ETHE1 persulfide dioxygenase
  F-box protein 6
  ferredoxin 2
  FKBP prolyl isomerase 7
  glutathione S-transferase omega 1
  guanine monophosphate synthase
  HEXIM P-TEFb complex subunit 1
  lebercilin LCA5
  leucine rich repeat kinase 2
  mediator complex subunit 20
  microcephalin 1
  mitogen-activated protein kinase 13
  MT-RNR2 like 1
  N-acetylneuraminate synthase
  NAD(P)HX epimerase
  neuron navigator 1
  nitrilase family member 2
  nuclear receptor subfamily 2 group C member 2
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  peptidase, mitochondrial processing subunit alpha
  peptidase, mitochondrial processing subunit beta
  perilipin 3
  peroxiredoxin 2
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 4
  protein O-glucosyltransferase 3
  radixin
  regulatory associated protein of MTOR complex 1
  SET domain bifurcated histone lysine methyltransferase 1
  small ubiquitin like modifier 4
  stress induced phosphoprotein 1
  succinate-CoA ligase GDP/ADP-forming subunit alpha
  succinate-CoA ligase GDP-forming subunit beta
  superoxide dismutase 1
  TLE family member 3, transcriptional corepressor
  TNFAIP3 interacting protein 2
  triosephosphate isomerase 1
  tumor protein p53
  ubiquitin C
  ubiquitin conjugating enzyme E2 L6
  ubiquitin conjugating enzyme E2 M
  ubiquitin conjugating enzyme E2 N
  unc-119 lipid binding chaperone
  vir like m6A methyltransferase associated
  WD repeat domain, phosphoinositide interacting 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.