PPP2R2A, protein phosphatase 2 regulatory subunit Balpha

PPP2R2A, protein phosphatase 2 regulatory subunit Balpha

• The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

• Gene Synonyms (serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, protein phosphatase 2, regulatory subunit B, alpha, B55A, B55ALPHA, PR52A, PR55A, PR55alpha,)
• NCBI Gene ID: 5520
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VJT0
  UNIPROT ID#>>P63151
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 2 regulatory subunit Balpha interacts with:

• AAR2 splicing factor
  Abelson helper integration site 1
  ATP binding cassette subfamily E member 1
  BCL2 like 14
  cell cycle and apoptosis regulator 2
  cell division cycle associated 4
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  checkpoint kinase 2
  chromosome 1 open reading frame 131
  crooked neck pre-mRNA splicing factor 1
  cullin 3
  cytidine monophosphate N-acetylneuraminic acid synthetase
  derlin 1
  dual specificity phosphatase 10
  dual specificity phosphatase 13
  dual specificity phosphatase 19
  ECSIT signaling integrator
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  endoplasmic reticulum protein 44
  exportin 1
  family with sequence similarity 107 member A
  family with sequence similarity 122A
  F-box and leucine rich repeat protein 16
  F-box and leucine-rich repeat protein 16
  F-box and WD repeat domain containing 8
  heat shock protein family A (Hsp70) member 4 like
  histone deacetylase 5
  immediate early response 2
  immediate early response 5
  kinase suppressor of ras 1
  large tumor suppressor kinase 2
  LEO1 homolog, Paf1/RNA polymerase II complex component
  mediator complex subunit 10
  Mtr4 exosome RNA helicase
  NADH:ubiquinone oxidoreductase complex assembly factor 1
  neutrophil cytosolic factor 1
  nitric oxide synthase interacting protein
  N-myc downstream regulated 1
  non-SMC condensin II complex subunit D3
  nucleotide binding oligomerization domain containing 2
  obscurin like cytoskeletal adaptor 1
  pelota mRNA surveillance and ribosome rescue factor
  PH domain and leucine rich repeat protein phosphatase 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  proteasome 26S subunit, non-ATPase 12
  protein phosphatase 2 regulatory subunit Bbeta
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 2 regulatory subunit B'delta
  protein phosphatase 2 regulatory subunit Bgamma
  protein phosphatase 2 regulatory subunit B'gamma
  protein phosphatase 2, regulatory subunit A, alpha
  protein phosphatase 2, regulatory subunit B, delta
  protein phosphatase 3 catalytic subunit alpha
  protein phosphatase 4 catalytic subunit
  protein phosphatase methylesterase 1
  protein prenyltransferase alpha subunit repeat containing 1
  protein tyrosine phosphatase domain containing 1
  protein tyrosine phosphatase non-receptor type 14
  protein tyrosine phosphatase non-receptor type 7
  RAB11 family interacting protein 5
  Raf-1 proto-oncogene, serine/threonine kinase
  RecQ like helicase 4
  ribosomal protein S11
  ribosomal protein S13
  ribosomal protein S28
  ribosomal protein S6 kinase B1
  ribosomal protein S6 kinase B2
  RNA binding motif protein 17
  RNA binding motif protein 7
  RRN3 homolog, RNA polymerase I transcription factor
  RuvB-like protein 2
  S100 calcium binding protein A7
  S100 calcium binding protein A8
  S100 calcium binding protein A9
  SERTA domain containing 4
  SMAD specific E3 ubiquitin protein ligase 1
  small nuclear RNA activating complex polypeptide 1
  snail family transcriptional repressor 1
  striatin 3
  TAFA chemokine like family member 3
  t-complex 1
  tensin 2
  THUMP domain containing 1
  transcription activation suppressor
  transcription elongation factor A like 1
  transforming growth factor beta receptor 1
  tubulin alpha 4a
  tyrosyl-tRNA synthetase 1
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 M
  VANGL planar cell polarity 1
  vir like m6A methyltransferase associated
  WD repeat domain 4
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger and BTB domain containing 38
  zinc finger CCHC-type containing 8
  zinc finger protein 574

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.