PPP2R5A, protein phosphatase 2 regulatory subunit B'alpha

PPP2R5A, protein phosphatase 2 regulatory subunit B'alpha

• The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

• Gene Synonyms (serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PP2A B subunit isoform R5-alpha, PP2A, B subunit, B' alpha isoform, PP2A, B subunit, B56 alpha isoform, PP2A, B subunit, PR61 alpha isoform, PP2A, B subunit, R5 alpha isoform, PR61alpha, protein phosphatase 2 regulatory subunit B', alpha, protein phosphatase 2, regulatory subunit B (B56), alpha isoform, protein phosphatase 2, regulatory subunit B', alpha isoform, serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform, B56A, B56alpha, PR61A,)
• NCBI Gene ID: 5525
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15172
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 2 regulatory subunit B'alpha interacts with:

• axin 1
  axin 2
  bestrophin 1
  checkpoint kinase 2
  chromobox 5
  chromosome 1 open reading frame 21
  cyclin G1
  DAZ interacting zinc finger protein 1
  eukaryotic translation initiation factor 2 alpha kinase 2
  extra spindle pole bodies like 1, separase
  FA core complex associated protein 20
  family with sequence similarity 43 member A
  G protein nucleolar 3
  glutamate rich 4
  pleckstrin homology domain containing A4
  proline rich 14
  protein phosphatase 2 regulatory subunit Bdelta
  protein phosphatase 2 regulatory subunit B'delta
  protein phosphatase 2 regulatory subunit B'gamma
  protein phosphatase 2, regulatory subunit A, alpha
  PTPRF interacting protein alpha 1
  PTTG1 regulator of sister chromatid separation, securin
  SHC adaptor protein 1
  shiftless antiviral inhibitor of ribosomal frameshifting
  shugoshin 1
  shugoshin 1
  shugoshin 2A
  suppressor of glucose, autophagy associated 1
  tripartite motif containing 25
  troponin T2, cardiac type
  tumor protein p63
  ubiquitin conjugating enzyme E2 S
  USH1 protein network component harmonin binding protein 1
  Wnt family member 3A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.