PREP, prolyl endopeptidase

PREP, prolyl endopeptidase

• The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008]

• Gene Synonyms (prolyl endopeptidase, dJ355L5.1 (prolyl endopeptidase), post-proline cleaving enzyme, prolyl oligopeptidase, PE, PEP,)
• NCBI Gene ID: 5550
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B2RAH7
  UNIPROT ID#>>P48147
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prolyl endopeptidase interacts with:

• aryl hydrocarbon receptor interacting protein
  heat shock protein family H (Hsp110) member 1
  inositol-3-phosphate synthase 1
  kinesin family member 3A
  mitochondrial ribosome associated GTPase 2
  neutral sphingomyelinase activation associated factor
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  potassium voltage-gated channel subfamily A regulatory beta subunit 2
  protein tyrosine phosphatase 4A1
  quinoid dihydropteridine reductase
  rhophilin Rho GTPase binding protein 1
  shugoshin 2
  sirtuin 7
  SUN domain containing ossification factor
  synuclein alpha
  tachykinin precursor 1
  threonyl-tRNA synthetase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.