PRKCSH, protein kinase C substrate 80K-H

PRKCSH, protein kinase C substrate 80K-H

• This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

• Gene Synonyms (glucosidase 2 subunit beta, AGE-binding receptor 2, advanced glycation end-product receptor 2, glucosidase II subunit beta, hepatocystin, protein kinase C substrate 60.1 kDa protein heavy chain, protein kinase C substrate, 80 Kda protein, AGE-R2, G19P1, GIIB, PCLD, PCLD1, PKCSH, PLD1, VASAP-60,)
• NCBI Gene ID: 5589
• Species: Homo sapiens (Human)
• UNIPROT ID#>>K7ELL7
  UNIPROT ID#>>P14314
  UNIPROT ID#>>B4DJQ5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein kinase C substrate 80K-H interacts with:

• anaphase promoting complex subunit 7
  anterior gradient 2, protein disulphide isomerase family member
  armadillo repeat containing X-linked 3
  aurora kinase A
  calreticulin 3
  COPI coat complex subunit gamma 1
  cullin 7
  cytochrome b5 type B
  DENN domain containing 6A
  endoplasmic reticulum lectin 1
  ER degradation enhancing alpha-mannosidase like protein 3
  fucose kinase
  glucosidase II alpha subunit
  glucosylceramidase beta 3 (gene/pseudogene)
  glutamine rich 1
  guided entry of tail-anchored proteins factor 4
  heat shock protein 90 beta family member 1
  importin 9
  integrator complex subunit 7
  nucleoporin 153
  phosphoethanolamine/phosphocholine phosphatase 1
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  pitrilysin metallopeptidase 1
  plasminogen receptor with a C-terminal lysine
  polyribonucleotide nucleotidyltransferase 1
  POP4 homolog, ribonuclease P/MRP subunit
  potassium channel tetramerization domain containing 10
  protein kinase C zeta
  protein tyrosine phosphatase receptor type C
  protein tyrosine phosphatase receptor type E
  protein tyrosine phosphatase receptor type N
  protein tyrosine phosphatase receptor type O
  PTEN induced kinase 1
  RAN binding protein 6
  regulator of G protein signaling 2
  ribosomal protein S6
  serrate, RNA effector molecule
  solute carrier family 27 member 2
  superoxide dismutase 1
  synaptojanin 2 binding protein
  syntaxin binding protein 3
  tectonic family member 1
  tectonic family member 3
  tripartite motif containing 25
  TSC complex subunit 2
  tubulin alpha 1a
  tubulin alpha 4a
  tubulin beta 3 class III
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin conjugating enzyme E2 M
  vir like m6A methyltransferase associated
  vitamin D receptor
  ZW10 interactor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.