- Gene Overview
- Interaction Network
- Sequence Verification
ABCD4, ATP binding cassette subfamily D member 4
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]
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Gene Synonyms (lysosomal cobalamin transporter ABCD4, ATP-binding cassette sub-family D member 4, 69 kDa peroxisomal ABC-transporter, ATP-binding cassette, sub-family D (ALD), member 4, PMP70-related protein, PXMP1-L, peroxisomal membrane protein 69, ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L,)
- NCBI Gene ID:
5826
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O14678
UNIPROT ID#>>A0A024R6B9
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for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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ATP binding cassette subfamily D member 4 interacts with:
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