RAP1B, RAP1B, member of RAS oncogene family

RAP1B, RAP1B, member of RAS oncogene family

• This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]

• Gene Synonyms (ras-related protein Rap-1b, GTP-binding protein smg p21B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, small GTP binding protein, K-REV, RAL1B,)
• NCBI Gene ID: 5908
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7ZAY2
  UNIPROT ID#>>A0A024RB87
  UNIPROT ID#>>P61224
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAP1B, member of RAS oncogene family interacts with:

• adaptor related protein complex 3 subunit mu 1
  alanyl-tRNA synthetase 2, mitochondrial
  ATPase H+ transporting accessory protein 2
  chaperonin containing TCP1 subunit 7
  coronin, actin binding protein 1C
  cysteine sulfinic acid decarboxylase
  dicer 1, ribonuclease III
  dimethylarginine dimethylaminohydrolase 2
  Fas associated factor 1
  filamin, beta
  GAR1 ribonucleoprotein
  KIAA1191
  ligand dependent nuclear receptor interacting factor 1
  LIM domain and actin binding 1
  LIM domain and actin binding 1
  lysine methyltransferase 2B
  mannosyl-oligosaccharide glucosidase
  microtubule associated scaffold protein 2
  mitochondrial ribosomal protein S35
  NCK associated protein 5 like
  nuclear receptor binding protein 2
  phospholipid phosphatase related 1
  pleckstrin homology and RUN domain containing M1
  proton activated chloride channel 1
  RAB7A, member RAS oncogene family
  RAB7B, member RAS oncogene family
  RAB8B, member RAS oncogene family
  RAP1 GTPase activating protein
  Rap1 GTPase-GDP dissociation stimulator 1
  Ras association domain family member 5
  RAS like family 10 member A
  regulator of G protein signaling 2
  regulatory associated protein of MTOR complex 1
  retinal degeneration 3, GUCY2D regulator
  stromal cell derived factor 4
  syntaxin 12
  syntaxin 7
  TLE family member 1, transcriptional corepressor
  tripartite motif containing 25
  tripartite motif containing 28
  tRNA splicing endonuclease subunit 2
  tumor protein p53
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin protein ligase E3 component n-recognin 4
  ubiquitin specific peptidase 32
  unc-119 lipid binding chaperone
  vascular cell adhesion molecule 1
  WD repeat containing antisense to TP53
  X-ray repair cross complementing 1
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 135

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.