PLAAT4, phospholipase A and acyltransferase 4

PLAAT4, phospholipase A and acyltransferase 4

• Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]

• Gene Synonyms (phospholipase A and acyltransferase 4, HRAS-like suppressor 4, RAR-responsive protein TIG3, phospholipase A/acyltransferase-4, retinoic acid receptor responder (tazarotene induced) 3, retinoic acid receptor responder 3, retinoic acid receptor responder protein 3, retinoic acid-inducible gene 1, retinoid-inducible gene 1 protein, tazarotene-induced gene 3 protein, HRASLS4, HRSL4, PLA1/2-3, PLAAT-4, RARRES3, RIG1, TIG3,)
• NCBI Gene ID: 5920
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UL19
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase A and acyltransferase 4 interacts with:

• mitochondrial antiviral signaling protein
  phosphoinositide-3-kinase regulatory subunit 3
  ring finger protein 123
  ring finger protein 135
  small glutamine rich tetratricopeptide repeat containing alpha
  syndecan 4
  T cell receptor associated transmembrane adaptor 1
  TNF alpha induced protein 3
  transglutaminase 1
  tripartite motif containing 25
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  ubiquitin conjugating enzyme E2 I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.