CCL13, C-C motif chemokine ligand 13

CCL13, C-C motif chemokine ligand 13

• This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]

• Gene Synonyms (C-C motif chemokine 13, CK-beta-10, chemokine (C-C motif) ligand 13, monocyte chemoattractant protein 4, monocyte chemotactic protein 4, new CC chemokine 1, small inducible cytokine subfamily A (Cys-Cys), member 13, small-inducible cytokine A13, CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1,)
• NCBI Gene ID: 6357
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99616
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-C motif chemokine ligand 13 interacts with:

• atypical chemokine receptor 4
  C-C motif chemokine receptor 2
  nucleotide binding oligomerization domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.