- Gene Overview
- Interaction Network
- Sequence Verification
SGCG, sarcoglycan gamma
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This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
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Gene Synonyms (gamma-sarcoglycan, 35 kDa dystrophin-associated glycoprotein, 35kD dystrophin-associated glycoprotein, sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein), 35DAG, A4, DAGA4, DMDA, DMDA1, LGMD2C, LGMDR5, MAM, SCARMD2, SCG3, gamma-SG,)
- NCBI Gene ID:
6445
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q13326
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
sarcoglycan gamma interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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