SLC4A2, solute carrier family 4 member 2

SLC4A2, solute carrier family 4 member 2

• This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. [provided by RefSeq, Nov 2016]

• Gene Synonyms (anion exchange protein 2, anion exchanger 2 type a, anion exchanger 2 type b1, anion exchanger 2 type b2, erythrocyte membrane protein band 3-like 1, non-erythroid band 3-like protein, solute carrier family 4 (anion exchanger), member 2, AE2, BND3L, EPB3L1, HKB3, NBND3,)
• NCBI Gene ID: 6522
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P04920
  UNIPROT ID#>>Q59GF1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 4 member 2 interacts with:

• atlastin GTPase 3
  cellular communication network factor 1
  elongation factor for RNA polymerase II 2
  G protein-coupled receptor 52
  galectin 9C
  IQ motif containing GTPase activating protein 3
  KDEL endoplasmic reticulum protein retention receptor 3
  kinesin family member 2C
  limb development membrane protein 1 like
  myosin, heavy polypeptide 10, non-muscle
  nuclear RNA export factor 1
  phosphatase, orphan 1
  reticulophagy regulator family member 3
  SAM pointed domain containing ETS transcription factor
  solute carrier family 39 member 4
  solute carrier family 39 member 8
  solute carrier family 4 member 8
  steroid receptor associated and regulated protein
  THO complex 2
  vacuolar protein sorting 4B
  xenotropic and polytropic retrovirus receptor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.