SMARCA1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

SMARCA1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

• This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Gene Synonyms (probable global transcription activator SNF2L1, ATP-dependent helicase SMARCA1, SNF2-like 1, global transcription activator homologous sequence, nucleosome-remodeling factor subunit SNF2L, sucrose nonfermenting 2-like protein 1, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SNF2LT, SWI, SWI2, hSNF2L,)
• NCBI Gene ID: 6594
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7ZLQ5
  UNIPROT ID#>>A0A0A0MRP6
  UNIPROT ID#>>P28370
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 interacts with:

• AT-rich interaction domain 1B
  bromodomain adjacent to zinc finger domain 1B
  chromosome 17 open reading frame 49
  cyclic GMP-AMP synthase
  DEF6 guanine nucleotide exchange factor
  DExD-box helicase 21
  DNA polymerase epsilon 3, accessory subunit
  embryonic ectoderm development
  forkhead box J2
  forkhead box Q1
  G3BP stress granule assembly factor 1
  H3 clustered histone 1
  indoleamine 2,3-dioxygenase 2
  innate immunity activator
  macroH2A.1 histone
  Nanog homeobox
  nuclear factor of activated T cells 2 interacting protein
  pleckstrin homology domain containing A4
  RAD18 E3 ubiquitin protein ligase
  RecQ like helicase 4
  regulatory factor X associated ankyrin containing protein
  RuvB like AAA ATPase 1
  SET domain containing 1A, histone lysine methyltransferase
  staufen double-stranded RNA binding protein 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
  TCF3 fusion partner
  TEA domain transcription factor 2
  transmembrane protein 128
  tripartite motif containing 28
  upstream transcription factor 1
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.