CACNB1, calcium voltage-gated channel auxiliary subunit beta 1

CACNB1, calcium voltage-gated channel auxiliary subunit beta 1

• The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (voltage-dependent L-type calcium channel subunit beta-1, calcium channel voltage-dependent subunit beta 1, calcium channel, L type, beta 1 polypeptide, calcium channel, voltage-dependent, beta 1 subunit, dihydropyridine-sensitive L-type, calcium channel beta-1 subunit, CAB1, CACNLB1, CCHLB1,)
• NCBI Gene ID: 782
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q02641
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

calcium voltage-gated channel auxiliary subunit beta 1 interacts with:

• atrophin 1
  CACN subunit beta associated regulatory protein
  calcium voltage-gated channel auxiliary subunit beta 2
  calcium voltage-gated channel auxiliary subunit beta 3
  C-terminal binding protein 2
  dynein light chain LC8-type 1
  kelch like family member 15
  NEDD4 like E3 ubiquitin protein ligase
  RRAD and GEM like GTPase 1
  SRSF protein kinase 1
  WD repeat domain 75

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.