CALCR, calcitonin receptor

CALCR, calcitonin receptor

• This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

• Gene Synonyms (calcitonin receptor, CRT, CT-R, CTR, CTR1,)
• NCBI Gene ID: 799
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30988
  UNIPROT ID#>>A0A0C4DG16
  UNIPROT ID#>>A0A0A0MRG0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

calcitonin receptor interacts with:

• calmodulin 1
  filamin A
  G protein-coupled receptor associated sorting protein 1
  G protein-coupled receptor associated sorting protein 2
  LDL receptor related protein 1
  mannose binding lectin 2
  receptor activity modifying protein 1
  receptor activity modifying protein 3
  sequestosome 1
  thrombospondin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.