DENND1C, DENN domain containing 1C

DENND1C, DENN domain containing 1C

• The protein encoded by this gene functions as a guanine nucleotide exchange factor for the early endosomal small GTPase RAB35, which regulates endosomal membrane trafficking and is involved in actin polymerization. The encoded protein activates RAB35 by promoting the exchange of RAB35-bound GDP for GTP. This gene may play a role in linking RAB35 activation with the clathrin machinery. [provided by RefSeq, May 2017]

• Gene Synonyms (DENN domain-containing protein 1C, DENN/MADD domain containing 1C, connecdenn 3, family with sequence similarity 31, member C, FAM31C,)
• NCBI Gene ID: 79958
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IV53
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DENN domain containing 1C interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.