DYRK3, dual specificity tyrosine phosphorylation regulated kinase 3

DYRK3, dual specificity tyrosine phosphorylation regulated kinase 3

• This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dual specificity tyrosine-phosphorylation-regulated kinase 3, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5, protein kinase Dyrk3, regulatory erythroid kinase, DYRK5, RED, REDK, hYAK3-2,)
• NCBI Gene ID: 8444
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43781
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dual specificity tyrosine phosphorylation regulated kinase 3 interacts with:

• F-box protein 25
  golgi reassembly stacking protein 2
  NEDD4 like E3 ubiquitin protein ligase
  sirtuin 1
  SMU1 DNA replication regulator and spliceosomal factor

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