DYRK2, dual specificity tyrosine phosphorylation regulated kinase 2

DYRK2, dual specificity tyrosine phosphorylation regulated kinase 2

• DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dual specificity tyrosine-phosphorylation-regulated kinase 2, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2,)
• NCBI Gene ID: 8445
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92630
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dual specificity tyrosine phosphorylation regulated kinase 2 interacts with:

• A-kinase anchoring protein 12
  centriolar coiled-coil protein 110
  centrosomal protein 78
  DDB1 and CUL4 associated factor 1
  DDB1 and CUL4 associated factor 5
  DDB1 and CUL4 associated factor 7
  dual specificity tyrosine phosphorylation regulated kinase 4
  eukaryotic translation initiation factor 2B subunit epsilon
  IKAROS family zinc finger 1
  katanin catalytic subunit A1
  kinesin family member 3B
  KxDL motif containing 1
  leucine rich repeat kinase 2
  leucine zipper tumor suppressor 2
  modulator of apoptosis 1
  nuclear receptor subfamily 1 group I member 2
  RAD54 homolog B
  RB1 inducible coiled-coil 1
  RBMX like 2
  ring finger protein 8
  salvador family WW domain containing protein 1
  single stranded DNA binding protein 2
  TANK binding kinase 1
  tubulin alpha 1c
  ubiquitin protein ligase E3 component n-recognin 5
  WD repeat domain 62
  X-prolyl aminopeptidase 3
  zinc finger and BTB domain containing 9

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.