APOL1, apolipoprotein L1

APOL1, apolipoprotein L1

• This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

• Gene Synonyms (apolipoprotein L1, apolipoprotein L 1, apolipoprotein L1-B3, APO-L, APOL, APOL-I, FSGS4,)
• NCBI Gene ID: 8542
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B1AH95
  UNIPROT ID#>>Q2KHQ6
  UNIPROT ID#>>O14791
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

apolipoprotein L1 interacts with:

• cell division cycle 23

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.