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CES2, carboxylesterase 2

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CES2, carboxylesterase 2

  • This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]

  • Gene Synonyms (cocaine esterase, carboxylesterase 2 (intestine, liver), intestinal carboxylesterase; liver carboxylesterase-2, methylumbelliferyl-acetate deacetylase 2, CE-2, CES2A1, PCE-2, iCE,)
  • NCBI Gene ID: 8824
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>O00748
    UNIPROT ID#>>A0A024R6X1
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carboxylesterase 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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