HS3ST1, heparan sulfate-glucosamine 3-sulfotransferase 1

HS3ST1, heparan sulfate-glucosamine 3-sulfotransferase 1

• Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (heparan sulfate glucosamine 3-O-sulfotransferase 1, 3-OST-1, h3-OST-1, heparan sulfate (glucosamine) 3-O-sulfotransferase 1, heparan sulfate 3-O-sulfotransferase 1, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1, heparin-glucosamine 3-O-sulfotransferase, 3OST, 3OST1,)
• NCBI Gene ID: 9957
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14792
  UNIPROT ID#>>A0A024R9R4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

heparan sulfate-glucosamine 3-sulfotransferase 1 interacts with:

• leucine rich repeat containing G protein-coupled receptor 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.