HGD, homogentisate 1,2-dioxygenase

HGD, homogentisate 1,2-dioxygenase

• This gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.[provided by RefSeq, May 2010]

• Gene Synonyms (homogentisate 1,2-dioxygenase, homogentisate oxidase, homogentisate oxygenase, homogentisic acid oxidase, homogentisicase, AKU, HGO,)
• NCBI Gene ID: 3081
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q93099
  UNIPROT ID#>>B3KW64
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

homogentisate 1,2-dioxygenase interacts with:

• GIT ArfGAP 2
  homogentisate 1,2-dioxygenase
  N-terminal glutamine amidase 1
  protocadherin gamma subfamily C, 3
  telomeric repeat binding factor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.