KLRC4, killer cell lectin like receptor C4

KLRC4, killer cell lectin like receptor C4

• Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010]

• Gene Synonyms (NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor, killer cell lectin-like receptor subfamily C, member 4, natual killer cell group 2-F, NKG2-F, NKG2F,)
• NCBI Gene ID: 8302
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43908
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

killer cell lectin like receptor C4 interacts with:

• killer cell lectin like receptor C4
  ribonucleic acid export 1
  UL16 binding protein 1

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