KLRG1, killer cell lectin like receptor G1

KLRG1, killer cell lectin like receptor G1

• Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]

• Gene Synonyms (killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, killer cell lectin-like receptor subfamily G, member 1, mast cell function-associated antigen (ITIM-containing), 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE,)
• NCBI Gene ID: 10219
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96E93
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

killer cell lectin like receptor G1 interacts with:

• ADP ribosylation factor like GTPase 13B
  glutathione peroxidase 8 (putative)
  leptin receptor overlapping transcript like 1
  mitochondrial rRNA methyltransferase 1
  spectrin repeat containing nuclear envelope family member 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.