POSTN, periostin

POSTN, periostin

• This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

• Gene Synonyms (OSF-2, OSF2, PDLPOSTN, PN, periostin, osteoblast specific factor 2 (fasciclin I-like), periodontal ligament-specific periostin, periostin, osteoblast specific factor,)
• NCBI Gene ID: 10631
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RDT5
  UNIPROT ID#>>B1ALD9
  UNIPROT ID#>>A0A024RDS2
  UNIPROT ID#>>Q15063
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

periostin interacts with:

• B9 domain containing 1
  MKS transition zone complex subunit 1
  myotubularin related protein 14
  transmembrane protein 231

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.