CYP46A1, cytochrome P450 family 46 subfamily A member 1

CYP46A1, cytochrome P450 family 46 subfamily A member 1

• This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CP46, CYP46, cholesterol 24-hydroxylase, CH24H, cholesterol 24-monooxygenase, cholesterol 24S-hydroxylase, cytochrome P450 46A1, cytochrome P450, family 46, subfamily A, polypeptide 1, cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase),)
• NCBI Gene ID: 10858
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6A2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cytochrome P450 family 46 subfamily A member 1 interacts with:

• Ras and Rab interactor 3

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