NMU, neuromedin U

NMU, neuromedin U

• This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]

• Gene Synonyms (neuromedin-U, neuromedin U precursor-related peptide/neuromedin U preproprotein, prepro-NMU,)
• NCBI Gene ID: 10874
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A250SH36
  UNIPROT ID#>>Q86WB6
  UNIPROT ID#>>A0A0B4J202
  UNIPROT ID#>>E9PDJ7
  UNIPROT ID#>>P48645
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

neuromedin U interacts with:

• cysteine rich tail 1
  doublecortin domain containing 2
  ectonucleoside triphosphate diphosphohydrolase 7
  glycoprotein integral membrane 1
  interleukin 20 receptor subunit beta
  keratin associated protein 10-6
  keratin associated protein 1-1
  keratin associated protein 12-3
  keratin associated protein 1-3
  keratin associated protein 1-5
  keratin associated protein 17-1
  MANSC domain containing 1
  MGAT4 family member C
  NBPF member 19
  neuromedin U receptor 2
  notch 2 N-terminal like A
  protocadherin 20
  protocadherin alpha 4
  tensin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.