LILRB5, leukocyte immunoglobulin like receptor B5

LILRB5, leukocyte immunoglobulin like receptor B5

• This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CD85C, LIR-8, LIR8, leukocyte immunoglobulin-like receptor subfamily B member 5, CD85 antigen-like family member C, leucocyte Ig-like receptor B5, leukocyte immunoglobulin-like receptor 8, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5,)
• NCBI Gene ID: 10990
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75023
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leukocyte immunoglobulin like receptor B5 interacts with:

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