CLIC1, chloride intracellular channel 1

CLIC1, chloride intracellular channel 1

• Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]

• Gene Synonyms (chloride intracellular channel protein 1, RNCC protein, chloride channel ABP, hRNCC, nuclear chloride ion channel 27, nuclear chloride ion channel protein, p64CLCP, regulatory nuclear chloride ion channel protein, CL1C1, CLCNL1, G6, NCC27,)
• NCBI Gene ID: 1192
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5SRT3
  UNIPROT ID#>>O00299
  UNIPROT ID#>>Q53FB0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chloride intracellular channel 1 interacts with:

• 3-hydroxyisobutyryl-CoA hydrolase
  6-phosphogluconolactonase
  actin, beta
  activating transcription factor 2
  ADP-ribosylserine hydrolase
  A-kinase anchoring protein 9
  aldehyde dehydrogenase 4 family member A1
  anillin actin binding protein
  anterior gradient 2, protein disulphide isomerase family member
  autophagy related 16 like 1
  calmodulin-like 3
  carnitine palmitoyltransferase 1A
  chloride intracellular channel 4
  component of oligomeric golgi complex 3
  coronin, actin binding protein 1C
  cullin 7
  cytidine/uridine monophosphate kinase 1
  damage specific DNA binding protein 1
  dimethylarginine dimethylaminohydrolase 1
  elongation factor Tu GTP binding domain containing 2
  enolase 1
  estrogen receptor 2
  EWS RNA binding protein 1
  FA complementation group D2
  F-box protein 6
  ferredoxin 1
  fibronectin 1
  FRA10A associated CGG repeat 1
  G protein-coupled receptor kinase 5
  glucose-6-phosphate isomerase
  glutathione S-transferase pi 1
  glycine cleavage system protein H
  glyoxalase domain containing 4
  glyoxylate and hydroxypyruvate reductase
  glypican 1
  GM2 ganglioside activator
  haloacid dehalogenase like hydrolase domain containing 3
  heparanase
  histidine triad nucleotide binding protein 2
  histone deacetylase 4
  HNF1 homeobox B
  hydroxysteroid 17-beta dehydrogenase 10
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  integrin subunit alpha 4
  IQ motif containing GTPase activating protein 1
  ISG15 ubiquitin like modifier
  isocitrate dehydrogenase (NADP(+)) 2
  leucine rich repeat kinase 2
  leucine zipper like transcription regulator 1
  LSM1 homolog, mRNA degradation associated
  mesenchyme homeobox 2
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
  MYC proto-oncogene, bHLH transcription factor
  myocilin
  myosin VC
  myosin, heavy polypeptide 10, non-muscle
  NADH:ubiquinone oxidoreductase subunit AB1
  neudesin neurotrophic factor
  neurotrophic receptor tyrosine kinase 1
  neurotrophin 4
  NHS like 2
  nucleoporin 62
  Parkinsonism associated deglycase
  peroxiredoxin 4
  peroxiredoxin 6
  phosphoglucomutase 1
  proline and serine rich 2
  proteasome 20S subunit alpha 1
  proteasome 20S subunit alpha 5
  proteasome 26S subunit, non-ATPase 10
  protein phosphatase 1 catalytic subunit gamma
  pyruvate dehyrogenase phosphatase catalytic subunit 1
  radixin
  ribosomal protein lateral stalk subunit P1
  selenophosphate synthetase 1
  small ubiquitin like modifier 4
  solute carrier family 33 member 1
  ST13 Hsp70 interacting protein
  stromal cell derived factor 2 like 1
  superoxide dismutase 1
  synaptopodin
  taperin
  thioredoxin like 1
  thyroid hormone receptor alpha
  trafficking protein particle complex 2
  transgelin 3
  triosephosphate isomerase 1
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin C-terminal hydrolase L1
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  WD repeat domain 77
  Yes1 associated transcriptional regulator
  YY1 associated factor 2
  zinc finger protein 184
  zinc finger protein 302

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.