Hprt, hypoxanthine guanine phosphoribosyl transferase

Hprt, hypoxanthine guanine phosphoribosyl transferase

• The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. [provided by RefSeq, Sep 2015]

• (No alternate names found)
• NCBI Gene ID: 15452
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>P00493
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hypoxanthine guanine phosphoribosyl transferase interacts with:

• cytotoxic granule-associated RNA binding protein 1
  eukaryotic translation initiation factor 6
  Fanconi anemia, complementation group D2
  integrin alpha 2b
  methylthioadenosine phosphorylase
  microtubule-associated protein tau
  NME/NM23 nucleoside diphosphate kinase 2
  prostaglandin E synthase 3
  syndecan binding protein
  WD and tetratricopeptide repeats 1
  WDYHV motif containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.