DRD1, dopamine receptor D1

DRD1, dopamine receptor D1

• This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DADR, DRD1A, D(1A) dopamine receptor, dopamine D1 receptor,)
• NCBI Gene ID: 1812
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P21728
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dopamine receptor D1 interacts with:

• calcyon neuron specific vesicular protein
  COPI coat complex subunit gamma 1
  COPI coat complex subunit gamma 2
  DnaJ heat shock protein family (Hsp40) member C14
  dopamine receptor D3
  erythrocyte membrane protein band 4.1 like 2
  filamin A
  glutamate ionotropic receptor NMDA type subunit 1
  growth hormone secretagogue receptor
  histamine receptor H3
  programmed cell death 6 interacting protein
  protein kinase cAMP-activated catalytic subunit alpha
  RAN binding protein 10
  RAN binding protein 9

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.